Examination of IgM rheumatoid factor (IgM-RF) and anti-cyclic citrullinated peptide antibody (anti-CCP Ab) in Japanese patients with palindromic rheumatism.
نویسندگان
چکیده
We have studied the serology of 6 patients with palindromic rheumatism. None of the patients fulfilled the classification criteria for rheumatoid arthritis at the entry; however, 4 out of the 6 patients were seropositive for IgM rheumatoid factor (IgM-RF) at entry. Sequential serological study was performed in 4 patients; IgM-RF changed from seronegative to seropositive in one patient, and the titer increased in another patient. Anti-cyclic citrullinated peptide antibody (anti-CCP Ab) at the entry was detected in only one of the 6 patients; that patient later developed RA. Although follow-up is necessary, the present study may suggest the importance of serological examination, especially anti-CCP Ab, in patients with palindromic rheumatism.
منابع مشابه
مقایسه ارزش تشخیصی Anti-cyclic citrullinated peptide antibody و فاکتور روماتوئید در تشخیص آرتریت روماتوئید
Abstract Background: Rheumatoid Arthritis, (RA) is a chronic inflammatory autoimmune disease with a progressive course requiring early diagnosis and treatment. The value of anti-cyclic citrullinated peptide antibodies (Anti-CCP) in the diagnosis of RA has been shown in several studies. The present study was designed to determine and compare the diagnostic value of Anti-CCP and rheumatoid fac...
متن کاملبررسی اندازه‌گیری آنتی‌بادی ضد سیترولین در تشخیص بیماران مبتلا به آرتریت روماتوئید و مقایسه با سایر بیماری‌های روماتیسمی و افراد به ظاهر سالم
Background and Aim: Rheumatoid arthritis (RA) is the most common autoimmune rheumatic disease, which requires specific diagnostic tests for it’s’ diagnosis. However specific and practical tests for its diagnosis are lacking. We evaluated the diagnostic accuracy of Anti-cyclic citrullinated peptide antibodies (Anti-CCP) in the diagnosis, prognosis and determination of the severity of RA.Mate...
متن کاملCONCISE REPORT Rheumatoid factor, but not anti-cyclic citrullinated peptide antibodies, is modulated by infliximab treatment in rheumatoid arthritis
Objectives: To analyse the effect of infliximab on IgM rheumatoid factor (RF) and anti-cyclic citrullinated peptide (CCP) antibodies, and determine whether baseline autoantibody titres (IgM RF and anti-CCP antibodies) are associated with changes in acute phase reactants. Patients and methods: 62 patients with refractory RA were treated with infliximab combined with methotrexate. At baseline and...
متن کاملAnti-cyclic citrullinated peptide antibodies and rheumatoid factor in leprosy patients with articular involvement.
The objective of the present research was to evaluate the usefulness of anti-cyclic citrullinated peptide (anti-CCP) antibodies and the IgM rheumatoid factor (IgM RF) test for the differential diagnosis of leprosy with articular involvement and rheumatoid arthritis (RA). Anti-CCP antibodies and IgM RF were measured in the sera of 158 leprosy patients (76 with and 82 without articular involvemen...
متن کاملCorrelation between anti-nuclear antibodies (ANA), rheumatoid factor (RF), anti-cyclic citrullinated peptides antibodies (Anti-CCP) and percentage and type of pulmonary involvement in patients with rheumatoid arthritis, Booali Hospital Tehran (2016-2
Background: Controlling the pulmonary involvement, as one of the most common extra-articular consequences in rheumatoid arthritis (RA), can improve the life quality and survival rate of patients. This study aimed to evaluate the correlation between disease-related inflammatory factors and the severity and type of lung involvement in patients, which is a practical step toward early detection and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Internal medicine
دوره 45 12 شماره
صفحات -
تاریخ انتشار 2006